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Although some of these low-penetrance genes appeared as good candidates for risk factors in the etiology of sporadic breast cancer, better designed and considerably larger studies than the majority of the studies conducted so far are evidently needed before any firm conclusions can be drawn.
28 31 Two of these studies examined the use of oral prophylaxis 28 30 while the other two considerably larger studies examined various regimens of intramuscular cefazolin.
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We contribute with results from a considerably larger study population in the North of Sweden and by showing trends in snus use over time.
The detection of 1q, 1p, 8q amplification events by aCGH and FISH suggests that a considerably larger study can be established where as a significantly larger cohort with clinicopathological data can be analyzed using only FISH analysis.
We report here findings in a considerably larger study population than in the two studies mentioned above, and we are the first to suggest that predictors for MV for more than 24 hours might also predict INSURE failure.
To investigate the reproducibility of these findings and to determine which STIs predict PSA elevation, we have now conducted a considerably larger study among US military members with stored serum in the Department of Defense serum repository (DoDSR).
In our considerably larger study of 383 astrocytomas Prx I was more frequently expressed in grade II and III tumors when compared to GBMs, but Prx VI expression did not have any statistically significant difference between these grades.
However, in a considerably larger study of 260,060 births to fathers employed at Sellafield, Dickinson et al. [ 7] reported that those men sired a greater proportion of boys than would be expected.
In this considerably larger study, we found a heterozygote OR estimate of 0.98 (95% CI = 0.94, 1.01; P = 0.21) and a homozygote OR estimate of 0.80 (95% CI = 0.69, 0.93; P = 0.004) with marginally significant evidence that the inverse association for homozygotes is greater than predicted by a multiplicative model (P = 0.04).
We have confirmed with considerably larger subject numbers in this study that the percentage of V α24+ NKT cells in cancer patients does not significantly differ to that in healthy donors when all cancer types are considered collectively (Yanagisawa et al, 2002).
Two considerably larger German studies [ 20, 21] reported less frequent and shorter duration of breastfeeding.
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