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Supporting this hypothesis, inhibition of Akt and MAPKs considerably inhibited 5-FU-induced TS upregulation, although not completely, which obviously indicates that these molecules are upstream of TS in the 5-FU signaling cascade.
Ketoconazole (100 µM) considerably inhibited the production of both metabolites, with 75% inhibition of 4′-OH 4-HPR and 85% inhibition of 4′-oxo 4-HPR.
Ketoconazole considerably inhibited the production of both metabolites, with 75% inhibition of 4′-OH 4-HPR and 85% inhibition of 4′-oxo 4-HPR at 100 µM.
This finding indicated that the recombination of the photogenerated charge carrier was considerably inhibited in the ZnO Sn2S3 heterostructures.
Use of XG as a stabilizer at high concentrations considerably inhibited the oxidation of WO in the prepared emulsions.
In conclusion, leishmania-cross reactive molecules of filarial parasite considerably inhibited leishmanial infection via Th1-mediated immune responses and NO production.
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For instance, AS can considerably inhibit invasion and metastasis in NSCLC.
It was concluded that lithiation of water-containing LixMnO2 considerably inhibits the liberation of water into the electrolyte solution.
Over all, the addition of CFG considerably inhibits the retrogradation of corn starch gels during long-term storage.
Difficulties with thermochemical processes due to low biomass density and development of complementary processes, as the Fisher-Tropsh process, considerably inhibit the establishment of these technologies.
This study revealed that the immobilization of antimicrobial aromatic terpenic components, such as carvacrol, involved in an innovative chemical structure designed to overcome their high volatility and thus the resulting limits to their use, can considerably inhibit yeast adhesion and subsequently delay biofilm formation.
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