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Considerably increased risk of ischemic events, in various organs including brain has already been documented in migraine [30].
Even if removed surgically, there remains a considerably increased risk of pancreatic cancer developing subsequently.
Individuals with severe Z α1-antitrypsin (AAT) deficiency have a considerably increased risk of developing chronic obstructive lung disease (COPD).
HIV-positive individuals in this cohort had a considerably increased risk of CVD compared with the ideal reference values.
Although few in number, women with negative HPV test and positive cytology had a considerably increased risk of CIN2+ (Fig. 3).
A history of a recent exacerbation within the last 3 months is associated with a considerably increased risk of a future exacerbation [relative risk (RR) 3.7] [ 9].
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Most recently, preliminary "real-life" data covering the first 12 to 16 weeks of therapy revealed considerably increased risk for severe and in some instances even lethal complications of PI-based treatment in cirrhotic patients [ 9, 10].
However, the clinical use of DOX is restricted considerably by an increased risk of cardiotoxicity associated with DOX-induced cardiomyocyte apoptosis [ 27- 29].
Impaired awareness of hypoglycemia renders patients at a threefold to sixfold increased risk of SH which considerably hampers their quality of life [ 13, 16, 19].
Depression is associated with considerably high mortality through suicide, medical illness, and increased risk of accidental death [ 6].
However, risk profiles based on a combination of risk variants lead to an appreciable increased risk of disease [ 35] and there is potential for the predictive power to increase considerably as more risk variants are detected [ 53].
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CEO of Professional Science Editing for Scientists @ prosciediting.com