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Here, we presented a considerably improved version that, among other changes, uses a novel LP formulation to optimally embed pathway networks into compact 2D lattice grids and provides a more flexible and user-friendly interface including ready-to-use pre-arranged 2D grid representations of pathway collections for now six organisms.
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Maybe even an improved version.
The improved version comes at a price.
Draw your own improved version.
I also am grateful to an anonymous referee for helpful feedback that considerably improved the final version of the entry.
Reviewer #3 [abridged]: I am fine with the revision – it is a considerably improved and focused version of the manuscript.
The constructive criticism and suggestions made by Jean-François Flot and two anonymous reviewers considerably improved the final version of the manuscript.
Finally, the maintenance of the prototrophs is explained by the uracil requirement; once this metabolite is supplemented, the remaining content of prototrophs is dramatically reduced.Reviewer #3 [abridged]: I am fine with the revision – it is a considerably improved and focused version of the manuscript.
I played with a bit of Gak over the past week and found it considerably improved over the previous version.
Although the speed of AmpliconNoise is considerably improved over its predecessor version (PyroNoise), it is still quite computational intensive.
From them it is concluded that eSS performs well with the benchmark problem, and that its performance is considerably improved by using its cooperative version, CeSS.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com