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Basolaterally applied TcdB possesses considerably higher potency in destroying epithelial integrity of monolayer than apically applied TcdB.
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Interestingly, basolaterally applied TcdA1 1874 exhibits considerably higher cytotoxic potency than apically applied or even full length TcdA.
The second assumption was substantiated by TER measurements showing that basolaterally applied TcdA1 1874 exhibits considerably higher cytotoxic potency than apically applied mutant or even full length TcdA, the latter being almost independent of the side of application.
However, even after administration of TOCP, the potency of MF was considerably higher than the theoretical irritation effect for a similar but potentially non-reactive counterpart to MF.
In vitro tests of these new TKIs show considerably higher activity in comparison with imatinib, with a 40-fold increased potency for nilotinib and a 325-fold for dasatinib [ 3].
The buried accessible surface area (ASA) for staurosporine bound to PKA is considerably higher than that of AMPPNP (330 vs 225 Å, respectively), which likely underlies their difference in inhibitory potency (Table 1).
Redwoods can grow considerably higher.
12. Considerably higher ticket prices.
Prices elsewhere may be considerably higher.
Now, however, that resolution is considerably higher.
Others put the value considerably higher.
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