In addition, we found the relative abundance of antisense transcripts is considerably higher for differentially expressed genes than those genes whose expression levels remain unchanged (p = 1.35E-7, Wilcox rank sum test; Figure 2B).
Conversely, a comparison of differentially expressed probesets (cancer vs. normal) identified in the bulk and LCM datasets, showed a considerably higher number of differentially expressed genes were found in the LCM data.
Although human keratinocytes express all four EP receptors, the level of expression of EP2 and EP3 is considerably higher than expression of EP1 or EP4 [ 66].
Statistically, subcluster-1 expressed considerably higher values (Min, Max and range) of RPR, RPPO and RBR than subcluster-2.
Since RU cells express considerably higher levels of HGF, and are an established tumor model, the in vivo efficacy of SU11274 was evaluated in a xenograft model using the RU-P melanoma cell line.
Among the differentially expressed transcripts, considerably higher numbers of ESTs were represented as either hypothetical (unknown) proteins or no GenBank match suggesting those may be novel genes associated with internal defense of abalone.
Consistent with this result, Cyclin D1 and c-Myc were expressed at considerably higher levels in tumors compared with normal mammary tissues (Fig. 6B).
The final interesting cluster of genes is cluster 4 (Table S3 (B4)), representing genes which generally increase in expression across all stages from hESC to EB to hESC-CM to FH, but which are expressed at considerably higher levels in the two older FH samples, 3 and 4 (at 20 and 21 weeks, respectively), than in FH1 and 2 (19 weeks each).
In patients who survived AMI, miR-155 and miR-380 were differentially expressed and considerably higher in patients who subsequently died due to cardiac causes [ 122].
