Baseline anti-cyclic citrullinated protein (anti-CCP) antibody concentrations were considerably greater in patients who were receiving MTX compared with those not receiving MTX.
There were also reports that pomegranate juice possessed considerably greater antioxidant capacity at much lower concentrations (>1000-fold >1000-fold than either grape or blueberry juice [ 73].
Measurements showed that the viscosity of the surfactant solutions increased with surfactant concentration, with the increase being considerably greater with the addition of ethanol as a co-surfactant.
For live tree islands, Hg concentrations in the surface head region were considerably greater than those in mid and tail region, and marsh soils.
It can be argued that, because induction of adverse effects in such models only occurs at levels of exposure considerably greater than those experienced by humans, effects at real-world concentrations of the chemical in question are unlikely to occur.
In contrast, there was a considerably greater cytotoxic effect when the drug was examined at low concentrations for periods similar to those described for the terminal phase of adriamycin clearance.
In adult mouse, GNE mRNA expression is highest in the liver followed by the lung and kidney [6] while Sia concentration measured in the spleen, brain and lung is considerably greater than in the liver or kidney [7].
The effect of zeta potential reduction is considerably greater in the case of the SA-96 /PAA suspension, mainly due to high concentration of dissociated carboxyl groups of polymer chains in the slipping plane area around the solid particle.
Cerebral drug penetration, as indicated by the ratio of the area under the methotrexate concentration-time curves in brain extracellular fluid and plasma, was considerably greater in contrast-enhanced tumor than in non-enhanced tumor.
Within weeks, the hemoglobin concentration of the neonate slowly declines and production of fetal hemoglobin (HbF), which possesses considerably greater affinity for oxygen than does adult hemoglobin, ceases.
