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Intracellular GSH content was reduced following 5-h incubation, but considerably elevated after 24 h, although GSH/GSSG ratio decreased in both cases.
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OS was lowest and the risk of death most considerably elevated in patients with increasing OPN levels after treatment (t1 to t2, rr = 3.8, 95%-CI [1.6-9]), followed by patients with stable post-treatment OPN levels (rr = 1.2, 95%-CI [.5-3]), p = .007, Figure 2C.
Incomplete seating on the bone may result in considerably elevated implant-bone micromotion and bone strains, thereby increasing the risk for TAR failure.
However, as compared to the least materially deprived neighbourhoods, rates were considerably elevated in the most materially deprived neighbourhoods.
This particular interspecies difference might be the result of the considerably elevated body temperature in torpor of bears.
Patients enrolling in later years had considerably elevated risks of LTFU compared to patients enrolled in 2004, aHR 6.18 (95% CI: 4.30 8.89; 2007 cohort).
Whereas bone mineral density (BMD) and OCN were significantly decreased in TH mice, RANKL, IL-6, and IL-17 expression and osteoclast activity were considerably elevated.
Patients intubated prior to primary PCI after cardiopulmonary resuscitation were excluded, because lactate levels have been shown to be considerably elevated in resuscitated patients [ 15, 16].
Accordingly, these participants have a considerably elevated risk of morbidity and mortality.
HFD-fed rats exhibited considerably elevated levels of serum ALT, AST and ALP.
Our patient had a considerably elevated FGF23 level with consequent renal phosphate wasting.
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