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One potential clue to the immunological differences between the WKY and GK strains is the considerably different expression in both liver and adipose tissue of MHC class II genes Db1, Bb, Ba.
Therefore, one may assume that a considerably different expression level is presented on recurrent tumours as compared with that of the primary PCa, as well as among progressive bone metastases.
In particular, genes encoding enzymes involved in flavonoid, theanine and caffeine pathways exhibited considerably different expression levels in tea compared to oil tea, which were also confirmed by quantitative RT-PCR (qRT-PCR).
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Both ZBTB4 and ZBTB38 are able to repress transcription in transfection assays, and whereas they display considerably different tissue expression profiles, both of them accumulate in the brain.
However, as our data demonstrate, one cell type has the potential to display considerably different gene expression patterns under different physiological conditions, making the transcriptome too labile to provide a consistent definition of cell type.
As expected, the use of two different algorithms resulted in data sets with considerably different distributions of normalized relative expression values.
In summary, gene expression variability is considerably different between organs and should be taken into account for study design.
However, the biological effects of ERβ are considerably different from those of ERα: ERβ expression alone, unlike hormone treatment, was not sufficient to drive cell proliferation [ 28].
However, the tissue distribution of the two proteins is considerably different, with TBC1D1 having little if any expression in adipocytes, and the highest level of expression in skeletal muscle [ 21, 22].
Analysis of gene structures and expression levels revealed that the general features of gene structure and expression of NAE and ANE genes were considerably different from those of AE genes.
Correspondingly, expression of these genes was considerably different at non-limiting iron concentration between Mo17 and B73.
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