Exact(2)
In vitro replication of the HA-expressing ILTV mutants was not affected, and infection of chickens revealed a reduced but still considerable virulence, similar to that of a UL50 gene deletion mutant without foreign gene insertion.
These bacilli could be restored to "considerable virulence in cattle" after passage through goats on his Marburg farm [5], [11].
Similar(58)
Therefore, it is clear that considerable variation in virulence exists between strains of the same serotype, which in turn highlights the contribution that serotype-independent factors play in virulence.
Recent studies have demonstrated that there are considerable variations in virulence, antigenic properties and nucleotide sequences among the field isolates of Akabane virus [ 15, 22, 24- 27].
For the pig lung pathogen Actinobacillus pleuropneumoniae, 15 serotypes with a considerable variation in virulence potential and immunogenicity have been identified.
The molecular data deduced from the complete genome sequences provides considerable knowledge of virulence factors in C. ulcerans that is increasingly recognized as an emerging pathogen.
STEC comprise a heterogeneous group of bacteria with considerable variation in virulence; and stx1-positive STEC, which are among the most frequent variants detected, has so far not been associated with HUS in Norway (unpublished data).
By combining experimental virology assays with mathematical modeling, we have described differences in growth properties from analysis in an in vitro system between viruses that exhibit considerable differences in their virulence in human infections.
More importantly however, as the number of ECF-sigma factors identified grows, attention is turning to their often considerable roles in the virulence of pathogenic organisms [46].
As the number of ECF-sigma factors identified grows, attention is turning to their often considerable roles in bacterial virulence [46].
There is considerable interest in identifying virulence factors that are Helicobacter pylori disease specific (eg, related to duodenal ulcer and not gastric cancer).
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