"considerable technical challenges" is a correct and usable phrase in written English.
It can be used to describe a situation where there are significant or difficult technical obstacles that need to be overcome. Example: The engineers were faced with considerable technical challenges when designing the new electric car, but they were able to successfully address them and create a revolutionary vehicle.
A passionate player of intense musicality, Ms. Weilerstein easily navigated the considerable technical challenges of the work and vividly conveyed its emotional depth, beginning with the weeping lines of the first movement.
Imaging these complex, three-dimensional ensembles presents considerable technical challenges, however.
Poorly water-soluble drug candidates often emerge from contemporary drug discovery programs, and present formulators with considerable technical challenges.
The effort faces considerable technical challenges but Milner said it was "based on technology that is available or available in the near future".
However, although such properties seem quite natural and are fairly easy to establish for arithmetical theories, they turn out to pose considerable technical challenges in the case of set theories, due to their transfinite hierarchies of sets and the extensionality axiom.
Genetic manipulation of primary macrophages and CD4+ T cells by shRNA methodologies poses considerable technical challenges.
Creating a probe that can function in such a wide range of conditions, and adapting it to those environments, is a considerable technical challenge.
However, due to the thousands of kilometers distance between each sites of the distributed radar system, how to optimally implement the Transmitting/Receiving (T/R) beams alignment in a great space using the narrow beam, which proposed a special and considerable technical challenge in the space surveillance area.
Set points of 0.2% are below the limit of those currently reported for scanning and represent a considerable technical challenge.
However, the levels of these species may be even lower than those of Aβ42; therefore, it will be a considerable technical challenge to develop assays that are sensitive enough to allow detection in the blood.
If these transactions are to happen – and the practice raises considerable ethical and technical challenges – then it is hard to imagine a better ghostwriter than David Lagercrantz, whose The Girl in the Spider's Web (MacLehose) convincingly extended the life of the late Stieg Larsson's great character, Lisbeth Salander.
