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(That strategy is being commercialized by Sigma Aldrich, according to principal R&D scientist Greg Davis, who notes the approach works with guides as far as 150 bases apart. "This is a key distinguishing point," he says, as it provides considerable targeting flexibility).
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Iain Overton, the executive director of Action on Armed Violence, warns that the Trump brand will be a considerable target for terrorists aiming to simultaneously damage the United States and Trump himself.
Proangiogenic NVU remodelling factors could be potential and considerable target for future drug design and delivery.
However, among ascomycete species with RIP, there is considerable target site variation (Galagan and Selker 2004; Clutterbuck 2011).
Some of them permitted Jeb Bush to stay in through South Carolina, and he spent that Bush faction's considerable resources targeting Rubio.
There has been considerable effort targeting inhaled carriers to macrophages, assuming that increasing intracellular antibiotic concentrations would increase sterilization.
The United States military has considerable experience in targeting surface-to-air missile batteries, but it is difficult to destroy all of the Taliban's antiaircraft guns and virtually impossible to eliminate the threat from shoulder-fired weapons.
Because mitochondrial dysfunction has been shown to play a major role in hypoxia-mediated injury and mitochondria are the major cellular source of ROS, there is considerable interest in targeting antioxidants to mitochondria [152].
There is considerable interest in targeting the TRAIL receptors using pro-apoptotic receptor agonists [2] and clinical trials using recombinant TRAIL and antibodies that target DR5 or DR4 are underway.
Because myostatin normally acts to limit muscle growth, there has been considerable interest in targeting this pathway to attempt to enhance muscle growth in human patients with muscle wasting and muscle degenerative diseases.
There is also considerable interest in targeting thermogenesis by brown adipose tissue to increase resting energy expenditure.
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