Sentence examples for considerable side effect from inspiring English sources

Their high cost and considerable side effect profile, however, have necessitated the establishment of guidelines for their use in these diseases in order to target the patient in whom they are likely to have the most benefit.

Despite pain being a considerable side effect, PDT offered the best cosmetic outcome and was the preferred treatment option by patients [ 42].

PP is a considerable side effect of long-term treatment with NSAIDs, most commonly naproxen, in patients with juvenile idiopathic arthritis (JIA) [ 8, 9, 23, 24].

Despite modest effectiveness and considerable side effects, psychotropic drugs are frequently prescribed for these neuropsychiatric symptoms.

This lack of effectiveness and the considerable side effects of D-penicillamine presumably have led to its low frequency of use.

The nontoxic nature of herbal medicines complements conventional treatment and excels over the synthetic drugs such as fluconazole, which are effective but come with considerable side effects and have high disease reoccurrence rate.

Considerable side effects and complications are seen with operative treatment.

However, many of them show considerable side effects.

Evidence-based prophylactic drugs may have considerable side effects.

In the above examined dose range and dosing regimens (acute and chronic) no considerable side effects were detected.

However, due to the narrow therapeutic window and considerable side effects associated with systemic dosing, Prialt is only administered intrathecally.