considerable sequence similarity

USAGE SUMMARY

The phrase "considerable sequence similarity" is correct and usable in written English.
It can be used in contexts related to biology, genetics, or bioinformatics when discussing the degree of similarity between sequences, such as DNA, RNA, or protein sequences. Example: "The analysis revealed considerable sequence similarity between the two proteins, suggesting a common evolutionary origin."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

27 human-written examples

Further, both 5′ and 3′ flanking regions of genes SLG1, SLG2 and SLG3 shared considerable sequence similarity.

Gene

The putative P. falciparum and P. vivax (PVX_098900.1) POFUT2 share considerable sequence similarity with H. sapiens and Caenorhabditis elegans (NP_001255070.1) POFUT2 and retain the catalytic residues of these enzymes (Supplementary Fig. 3).

Nature

Metazoans additionally possess VPS33B, which has considerable sequence similarity to VPS33A but does not integrate into CORVET or HOPS complexes and instead stably interacts with VIPAR.

Journal of Molecular Biology

Due to considerable sequence similarity with SPARC, SMOC2 may have analogous biological functions [39].

Plosone

This critical arginine residue is conserved in S. pombe Hip1, and indeed the whole WD repeat region of Hip1 and human HIRA exhibit considerable sequence similarity [7].

Plosone

At least 10 complete open reading frames with considerable sequence similarity to proteases of Baccilus subtilis have been identified in D. radiodurans [41], which are implicated herein as contributing to the pool of peptides needed to form antioxidant Mn2+ complexes.

Plosone

Human-verified similar examples from authoritative sources

Similar Expressions

33 human-written examples

Based on considerable sequence similarities of the 5'- and 3'-untranslated regions (UTR) of V2R genes primers were designed (Supporting Material Table S2) which allowed for the identification of some sequences encoding the N and C termini of mammalian V2R orthologs.

Plosone

The percentage of sequence identity observed between Omp3/Omp7 and the reference proteins was moderate and predominantly at the C-terminal domain, however, they showed considerable global sequence similarity, and thus we speculate that they may be similar at the structural level when they are exposed to the host immune system.

Plosone

Despite considerable sequence divergence (similarity ranged within 38-83%) the salmonid lectins contain highly conserved domains that, hypothetically, may cross-hybridize.

BMC Genomics

The three AtMDL proteins exhibit considerable pairwise sequence similarity with AtMDL1 and AtMDL2, showing a higher degree of relatedness to each other than to AtMDL3 (AtMDL1- AtMDL2: 60% identity, 75% similarity; AtMDL1- AtMDL3: 40% identity, 57% similarity; AtMDL2- AtMDL3: 50% identity, 69% similarity).

BMC Evolutionary Biology

As we also identified another MYC2 transcription factor (putatively named as MYC2-like; GenBank Accession number KC906192) with a considerable protein sequence similarity to MYC2, we tested if its transcript accumulation was affected in MYC2-VIGS plants.

BMC Plant Biology

Expert writing Tips

Best practice

When discussing sequence relationships, specify the percentage or E-value to quantify the degree of "considerable sequence similarity".

Common error

Do not use "considerable sequence similarity" without providing context or quantifiable metrics. Clarify which regions or domains exhibit the similarity.

Linguistic Context

The phrase "considerable sequence similarity" functions as a descriptive term. As Ludwig AI confirms, it denotes a notable degree of likeness between genetic sequences, often used to imply evolutionary or functional connections.

Expression frequency: Common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, "considerable sequence similarity" is a commonly used phrase in scientific contexts to describe a noteworthy resemblance between genetic sequences. As Ludwig AI confirms, its grammatical status is correct, and it primarily functions to highlight potential evolutionary or functional links. For precise scientific writing, quantify the degree of similarity with metrics like percentage identity or E-values. While authoritative sources like PlosOne and BMC Genomics frequently employ this phrase, remember to avoid vagueness by specifying the regions or domains exhibiting the similarity.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

significant sequence homology

Replaces "similarity" with "homology", implying shared ancestry.

high degree of sequence resemblance

Substitutes "similarity" with "resemblance", emphasizing visual likeness.

substantial sequence identity

Uses "identity" to highlight the extent of exact matches in the sequences.

notable sequence relatedness

Emphasizes the connection or relationship between sequences.

marked sequence alignment

Highlights the alignment process and the resulting similarity.

pronounced sequence conservation

Focuses on the preserved regions within the sequences.

appreciable sequence overlap

Highlights the regions where the sequences share common elements.

evident sequence parallels

Implies that the sequences run alongside each other in terms of features.

clear sequence correlation

Suggests a statistical relationship between the sequences.

observable sequence commonality

Focuses on the shared characteristics that can be observed in the sequences.

FAQs

How is "considerable sequence similarity" determined?

The determination of "considerable sequence similarity" often involves computational tools like BLAST, which provide scores (e.g., E-values, percentage identity) indicating the degree of similarity between sequences. These scores are then interpreted based on established thresholds within the specific research field.

What does "considerable sequence similarity" imply?

Generally, "considerable sequence similarity" suggests a potential evolutionary relationship, functional conservation, or structural relatedness between the sequences being compared. However, further investigation is usually required to confirm these implications.

What are some alternatives to "considerable sequence similarity"?

You can use alternatives like "significant sequence homology", "high degree of sequence resemblance", or "substantial sequence identity" depending on the specific context.

In what fields is "considerable sequence similarity" commonly used?

"Considerable sequence similarity" is frequently used in fields such as molecular biology, genetics, bioinformatics, and evolutionary biology to describe relationships between DNA, RNA, or protein sequences.