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Considerable sequence homology exists across different mammalian species.
There is considerable sequence conservation within the SET domain and within its flanking regions.
Bacterial 16S ribosomal RNA (rRNA) genes contain nine "hypervariable regions" (V1 V9) that demonstrate considerable sequence diversity among different bacteria.
Further, both 5′ and 3′ flanking regions of genes SLG1, SLG2 and SLG3 shared considerable sequence similarity.
Penicillin V acylases (PVAs) and bile salt hydrolases (BSHs) have considerable sequence and structural similarity; however, they vary significantly in their substrate specificity.
Metazoans additionally possess VPS33B, which has considerable sequence similarity to VPS33A but does not integrate into CORVET or HOPS complexes and instead stably interacts with VIPAR.
Although there is considerable sequence variation between the different bacterial PDFs, there are three strongly conserved motifs that together constitute a critical metal binding site.
Tumor necrosis factor-α-inducible protein 8 (TNfamily farely are very recently identified proteins which share considerable sequence homology to regulate cellular and immune homeostasis.
Due to considerable sequence similarity with SPARC, SMOC2 may have analogous biological functions [39].
JCV T-Ag has a considerable sequence homology with T-Ag's of BKV and SV40.
In particular, the neck regions align well in structure and contain considerable sequence identity as previously analyzed [9], [11].
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