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The latter has been proven to be a considerable risk factor for orthodontic root resorption [29].
Importantly, PSC is a considerable risk factor for the development of cholangiocarcinoma (CCA) that results from a malignant transformation of bile duct epithelial cells.
Mental health problems are common in young people with 75% of disorders beginning in adolescence and adolescent onset posing a considerable risk factor for long term psychological problems [ 1].
Although malnutrition has been associated with increased hospitalization, increased susceptibility to infection, reduced QOL, and increased mortality [ 49- 51], nutritional status evaluation may not be afforded sufficient attention in the field of chemotherapy-induced toxicity in patients with NSCLC, who themselves represent a considerable risk factor for complications and co-morbidities.
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In addition to familial disposition, somatic mutations in key genes pose as considerable risk factors for melanoma.
3, 4 Esophagectomy is a high-risk procedure with serious postoperative complications and a reported mortality rate ranging from 2 to 6%. 1, 3, 5 Moreover, esophageal cancer patients often have considerable risk factors for major surgery, including obesity and pulmonary and cardiovascular diseases.
Early in life, the expression of extreme BI, characterized by excessively inhibited responses to strangers or novel situations is a considerable risk-factor for the development of anxiety and depression [1] [3].
In pathogenesis of necrotizing enterocolitis (NEC), both oxidative stress and inflammation are considerable risk factors.
Moreover, amputation rates were significantly (p < 0.0001) lower in the becaplermin (4.9%) than in the control group (6.4%), despite the fact that patients receiving becaplermin had considerable adverse risk factors for healing (increased wound duration and size, increased wound grade at initial visit) (Margolis et al 2005b).
Blood glucose variability is receiving considerable attention as a new risk factor for coronary artery disease.
These results have important implications since non-alcoholic fatty liver disease is the most common liver disease in the population and is receiving considerable attention as an independent risk factor for cardiovascular disease.
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