The evaluation showed that the effort can lead to a considerable refinement of a given pre-clustering by the consequent exclusion of superfluous proteins from complex candidates.
Ozil, a playmaker of considerable refinement for Real Madrid and Germany, brings both excitement and status to Arsenal.
A trace (0.1 at.%) addition of Ge to a base Al 1.7Cu 0.3Mg alloy resulted in considerable refinement of the θ′ (Al2Cu) precipitate dispersion as well as stimulating the formation of 〈0 0 1〉α lath-shaped precipitates in a fine and uniform distribution.
Preoperative therapy strategy has been around for a long time, 17– 19 but it is only now that we are seeing some of the results of prospective evaluation, 20, 21 and the strategy needs considerable refinements and upgrades.
In spite of the considerable refinement in the definition of MCI, several clarifications might still be required in order for MCI to be considered as a helpful concept.
Conducted with considerable refinement by Christian Curnyn, the opera is for the most part finely sung.
An increase in peak current density resulted in considerable refinement in crystal size of the deposits.
Despite considerable refinement of MMIBI applications over the past three decades, a central challenge remains concerning the method of selecting ecological indicators for inclusion in MMIBI.
However, improvements in environmental sensors over the last 20 years have established the complexity of desert climates and the importance of microclimatic controls and allowed considerable refinement of experimental design.
It has become increasingly more evident that a considerable refinement of currently used reagents and conditions will be needed before an effective gene therapy strategy can be used in the treatment of human autoimmune diseases.
As discussed in the section "Future directions" below, estimation of volcanic volumes is one area where considerable refinement of the existing data sets could occur, although we note that similar calculations using volumes derived from Sherrod and Smith14 produce broadly comparable results (Supplementary Figures S1 and S2).
