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Given the substantial therapy costs and the considerable rate of side effects (especially skin toxicity), improved strategies for identifying responders are needed.
The considerable rate of side effects related to the use of higher doses of glucocorticoids or cyclophosphamide, the high rate of relapses on standard therapy regimens, and the fact that some EGPA patients either do not respond to CYC therapy or relapse shortly after CYC treatment underline the need for alternative therapies [ 9].
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The higher rate of side effects and potentially higher discontinuation rate should also be considered.
Otherwise, the rate of side effects from denosumab was roughly the same as from the placebo.
The vaccines had a high rate of side effects before their civilian use ended in 1972.
Thelin showed a lower rate of side effects than Tracleer, Encysive said.
The downside, however, is the increased rate of side effects.
Another important feature of schizophrenic patients that may influence their every-day functioning and performance, and result in a considerable number of side effects, is their antipsychotic medication.
However, a considerable rate of systemic adverse effects were associated with their use [5].
Tolerance and aesthetic quality of the correction obtained indicate considerable safety features and absence of side effects.
The Udvalg for Kliniske Undersøgelser (UKU) Side Effect Rating Scale [ 51] is used for registration of side effects.
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CEO of Professional Science Editing for Scientists @ prosciediting.com