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Because of the considerable published data linking metal-binding to the aggregation of Aβ, metal-chelation drugs have been proposed as a potential therapy for AD [40], [41].
Our data confirm differential expression during senescence of several miRNAs for which considerable published evidence suggests a role in regulating senescence or proliferation-associated pathways, including miR-34a [9], [10] [10] and miR-146a [12], [12] (Table 1).
We note that considerable published data from other labs supports the idea that Cdc42 itself can transit through the cytoplasm without GDI.
Considerable published evidence shows that with advanced age, production of ROS significantly increases in both the heart [ 5] and the vasculature [ 6].
There is considerable published data regarding the efficacy of plant extracts, but information on the toxicity of these natural resources is not sufficient [ 1].
Considerable published evidence suggests that interindividual variation in response to 5-FU results from variations in the thymidylate synthase (TS) mRNA expression levels of the tumour (Longley et al, 2003).
Similar(51)
Although not primarily a manufacturing centre, Bath also has considerable publishing and light engineering industries.
It constitutes, as nearly everybody knows, the third-largest industry in the country, and it is responsible for the existence of a considerable publishing business.
Moreover, because her songs had become hits for others, she was a source of considerable publishing revenue for her record companies.
The Department of Culture had a broad purview, overseeing cultural and demographic research, the construction of parks and playgrounds, and a considerable publishing wing.
Despite considerable data published on cognitive and behavioral disabilities in children with fetal alcohol spectrum disorders (FASD), relatively little information is available on behavioral or pharmacological interventions for alcohol-affected children.
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