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Considerable prolongation of heparin release was achieved with incorporation of heparin/chitosan nanocomplexes into the gelling systems.
Only in some cases considerable prolongation of lifespan was obtained and in organisms which are evolutionarily quite distant from mammals.
Conventional chemotherapy or combination of radio- and chemotherapy have been disappointingly ineffective and have not led to any considerable prolongation of survival.
In contrast, continuous infusions of the other 4-anilidopiperidine opioids result in accumulation and considerable prolongation of effect with increased duration of infusion [ 10], making these opioids intermediate-acting or long-acting agents during prolonged infusion.
There was considerable prolongation of graft survival in animals receiving CTLA4-KDEL-expressing DCs (median survival time > 100 days), when compared with that of animals treated with no DCs (12 days), unmodified DCs (11 days) or control GFP-transduced DCs (9 days) (Fig. 7C).
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In our study, the association between patients experiencing neutropenia and survival prolongation was considerable.
The management of metastatic breast cancer has evolved considerably in the last 5 6 years and a variety of treatments have been shown to impact on the natural history of this disease over this period, with demonstration of survival prolongation justifiably generating considerable excitement.
Prolongation of renal allograft survival a considerable challenge.
The period during which the growing fetus is protected in the uterus is characterized by a considerable range of variation among primate species, but it shows a general trend toward prolongation as one ascends the evolutionary scale.
The method uses a nonlinear prolongation operator.
Ravenel, M. P., The Gordon Bell Memorial Lecture, 1925, on "The Prolongation of Life.
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