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Reassortment of influenza virus genomes can lead to entirely novel strains with considerable pandemic potential (Neumann et al., 2009).
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During the influenza A(H1N1 pmd09 pandemic, considerable variability in administration of TIV and pandemic vaccines occurred, with some authorities recommending co-administration, and others recommending that TIV be given a month or more after the pandemic vaccine.
Pandemic H1N1 received considerable attention with strong media messages urging people to undergo vaccination and encouraging improved infection control efforts.
Pandemic nH1N1 received considerable attention with strong media messages urging people to be vaccinated and encouraging improved infection control efforts.
Despite the considerable media attention to the pandemic, a high proportion of adults in Australia poorly understood the fundamental aspects of transmission, symptoms, and impact.
Hospitals are expected to withstand considerable challenges during an influenza pandemic, including surge capacity, patient triage, infection control, delaying non-emergent surgical procedures, and expanding ICU capacities.
Therefore, the use of high-growth FPV reassortants with HA and NA proteins of circulating viruses generated on the basis of the cleavage mutants might be of considerable advantage especially in a pandemic situation where timely availability of large numbers of vaccine doses is of utmost importance for the immediate and efficient protection of vulnerable population groups.
14 Even during periods between pandemics, children experience considerable morbidity and mortality from influenza infection, and their role in virus transmission results in a much wider burden.
The novel influenza A pandemic virus (H1N1pdm) caused considerable morbidity and mortality worldwide in 2009.
Thus, even a relatively mild pandemic can have a considerable local and global impact, and inexpensive measures to reduce the effect of future pandemics remain an urgent priority.
The greatest threat, however, is during pandemics when most of the population is naïve and thus the pandemic could lead to considerable morbidity and mortality.
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CEO of Professional Science Editing for Scientists @ prosciediting.com