But Celebra is likely to have considerable "off-label use" — as physicians use it to replace narcotics for relief of moderate pain..
But Celebra is likely to have considerable "off-label use" — as physicians use it to replace narcotics for relief of moderate pain.
On the genomic scale, these nucleases still show considerable off-target activity though, posing a serious obstacle to the development of therapies.
ChIP-Seq not only revealed enriched binding of ZFPs to their intended sequence, but also considerable off-target binding, especially at promoter regions.
While interesting, it must be kept in mind that antagomiRs have considerable off-target effects and may also neutralize related, relevant microRNA with conserved "seed" sequences, although the antagomiR approach offers an easily applied and stable means of antagonizing microRNA function in a relatively specific fashion.
The head of an energy supply company with offices in Pennsylvania, Texas, New York, New Jersey, and Connecticut, Vague, 54, dedicates considerable off-duty time to the city's arts scene, serving as president of the Live Arts Festival and Philly Fringe.
Therefore, pan-agonists may have considerable off-pathway activation (or repression) that might be undesirable or teratogenic.
Again, agonists were found to have considerable off-target effects in the animal studies.
Sales of cars have reportedly gone up – spurred by fears of Greece heading either for the euro exit door or a Cyprus-style "bail-in" which might dock considerable amounts off holdings.
Although all mentioned CDS are not at levels reached during the summer and still a considerable way off, this recent rise threatens to undo the rally triggered by the ECB's OMT backstop announced in September which aims to assist struggling nations who need financial support.
