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In contrast to thymidine nucleosides, cytosine derivatives cause considerable obstacles when reacted with chlorophosphane 172: for instance, cycloSal modifications of 3TC or ddC were achieved in very low yields.
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Even when these vaccines and drugs become available, considerable obstacles remain to detecting influenza promptly and getting vaccination or drug therapy to the contacts of influenza patients.
OnLive faces considerable obstacles.
Yet there are considerable obstacles.
But they face considerable obstacles.
But CNN still faces some considerable obstacles.
Still, there are considerable obstacles to a protracted nominating battle.
Indeed, the efforts to open new clinics face considerable obstacles.
The chancellor said there were "very considerable obstacles" to nationalising RBS.
"Residents face considerable obstacles in providing their families with a healthy diet," he said.
But the proposal faces considerable obstacles, both in the State Legislature and the private sector.
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CEO of Professional Science Editing for Scientists @ prosciediting.com