It quickly earned a considerable number of likes.
Indeed, similar bioactivity profiles were observed for these compounds, indicating strong and consistent inhibitory activity for a considerable number of cell lines.
Taken all together, a considerable number of well-established lines of evidence have confirmed that flavonoids in citrus peel exhibit a remarkable spectrum of efficacious biological activities, particularly in antitumorigenesis.
The fact that the same allele was also present in a considerable number of vernalization insensitive (facultative) lines of the OSU CAP I, II and III (93 out of 129) suggests that this region could play a role in any of the multiple aspects of winter growth habit (e.g. low temperature tolerance or photoperiod sensitivity) since these are target traits in the OSU breeding program.
The observation of numerous strong optical-optical double resonance has shown that there are a considerable number of near coincidences between laser lines of CO2 and the absorption lines of formaldoxime molecule (CH2NOH).
There is a considerable number of well characterized human cancer cell lines, many of which can be grown as solid tumors (either subcutaneously or orthotopicaly) in immunodeficient mice.
However, median duration of the antibody therapy without detection of tumor progression was 43 weeks only, indicating a trastuzumab treatment in multiple lines in a considerable number of patients (see below).
Some authors have recently integrated a considerable number of high-throughput data from OS cell lines, either by miRNA vs mRNA expression profiles [ 39, 40] or vs CGH arrays [ 41] or by protein arrays [ 42], identifying miR-17/92 miR-17/92 39] or TGFbeta pathway [ 42] as cluster mediators.
First, the current annotation associated with a considerable number of probe sets may not be in line with current knowledge of the genome [6], [7].
In the second-line setting, a considerable number of trials using MMC plus continuous infusional 5-FU have been carried out demonstrating that the addition of MMC to 5-FU can overcome resistance to first-line chemotherapy in a distinct number of patients (Conti et al, 1995; Becker et al, 1997; Seitz et al, 1998; Chester et al, 2000; Tassinari et al, 2000; Grumett et al, 2001; Ross et al, 2002).
