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At first glance it seemed that the result of, for example, K-Means-R was as good as the result from ASAP, but the large number of species and the not less considerable number of clusters made the comparison difficult.
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A considerable number of clustering algorithms have been developed over the last few decades [17, 47, 48], including connectivity models [49] (i.e. hierarchical clustering), centroid models [50 52] (i.e. k-means algorithm) and density based models [16, 53, 54].
In conjunction with statistical analyses, routine genotyping allowed us to identify a considerable number of putative temporal clusters of listeriosis.
This result indicates that orthologous gene displacement has replaced a considerable number of genes in these clusters since the clusters separated from their common ancestor.
We found a high genetic potential for secondary metabolite production also in Gram-negative marine bacteria with genome sizes ranging from 4 to 6 Mb, with some strains reaching the considerable number of eight distinct PKS/NRPS clusters (Table 1 – NP.search).
The likely role of this putative protein is blood meal digestion, as astacins molecules have not been implicated in immune functions and a considerable number of transcripts constituting this cluster were derived from the blood-fed midgut cDNA library.
At SIS, recent samples were more influenced by the 'Nuuk' cluster although they still contained a considerable number of individuals assigning to the 'West' cluster.
The Mapman annotation network indicated that CitrusNet contained a considerable number of biological modules, and the clustering algorithm successfully grouped terms that were previously classified as multimeric complexes.
For example, a considerable number of genes regulated by rcsB were clustered in C2, but rcsB itself was clustered in C3, supporting the negative transcriptional change relationship between C2 and C3.
A large contribution of satellite DNA was noted in the P. subflavus genome (6%), as well as a considerable number of unidentifiable contigs across several repeat clusters.
Genus Shewanella of marine metal-reducing bacteria was highly populated with considerable number of annotated bPOPs in all the nine clusters.
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