Sentence examples for considerable methodological issues from inspiring English sources

There are however considerable methodological issues associated with these types of measure, and these are made more complex when they are applied in mental health and paediatric settings.

Falls research inevitably faces considerable methodological issues concerning reliable ascertainment, and even in this prospective data collection we had to rely on recall to some extent.

Considerable experience of methodological issues such as literature search, critical appraisal of identified studies and methods for summarising data has been gained and tools have been developed for the reviews and meta-analysis of RCTs [ 8].

22– 24 Considerable research focused on methodological issues of NMA has been published in recent years; however, a limited number of simulation studies have been conducted.

Three studies [ 26- 28] were all part of the Central Texas Field Trial and used the outcome parameter 'medically attended acute respiratory illness' (MAARI), which has considerable limitations, and also had other methodological issues (see Additional file 1 for more details).

As a result, considerable methodological challenges remain.

Some methodological issues require consideration.

However, there are some methodological issues that require consideration.

As a result, there is considerable methodological variation between studies.

In some clinical trials, biomarker changes were statistically significant and associated with clinical end points, but there is considerable heterogeneity between studies that are to some extent attributable to methodological issues.

Recent years have seen considerable methodological advances in methods for assigning cause of death in settings where death certificates are not routinely issued by physicians.