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The small organ size in these animals, together with limitations in blood sampling, poses considerable methodological challenges.
As a result, considerable methodological challenges remain.
This is possibly because of the considerable methodological challenges involved [ 6, 7].
Such large-scale evaluations of OHPC designs in practice settings are much warranted, but also associated with considerable methodological challenges.
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The reduced depth of the photic zone in most intertidal and shallow coastal sediments makes the characterization of its properties a considerable methodological challenge.
Dynamically addressing such risks therefore requires scaling across multiple hierarchical levels (i.e., from leaves to landscapes), which, as is described in more detailed in the following section, poses a considerable methodological challenge (see Seidl et al. 2013).
However, there are - and this will be discussed in the following - sometimes considerable conceptual and methodological challenges.
In conclusion, there are considerable technical and methodological challenges in conducting fNIRS studies during walking which can introduce inconsistencies in study findings.
10, 72 This review has demonstrated that the achievement of an accurate assessment of influenza vaccine effectiveness is fraught with considerable methodological and epidemiological challenges.
Although most of the models have potential to predict future trends depending on how the model is populated, the methodological challenges are considerable, and there is substantial need for further research and development.
Each comes with its own methodological challenges, and existing approaches and tools to do so can be costly to implement or require considerable technical knowledge and skill.
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