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An increase in extracellular fluid, if it is considerable, may be clinically apparent as edema, a swelling of the tissues by fluid, which can usually be displaced by firm pressure.
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Considerable underdosing results in ineffective treatment and the development of drug resistance, while considerable overdosing may be associated with toxic effects.
In very large organs with tracker action, considerable strength may be necessary to depress the keys.
Thus, considerable experimentation may be necessary in order to optimize a design.
Considerable noise may be generated when few cycles in the amplification are available to estimate peak efficiency.
Because of the large cross-sectional area of this part of the airway, considerable disease may be present in the bronchioles without affecting the expiratory flow rate.
Should it be directed backward, on the other hand, considerable difficulty may be encountered, and the head may have to be flexed or rotated artificially.
Dr. Camilli's paper tends to support the view that considerable oil may be lingering below the surface of the gulf.
Surviving in the business for a considerable period may be viewed as a success.
Considerable effort may be needed to develop and validate phenotyping algorithms.
If the improvement is considerable, savings may be made.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com