Sentence examples for considerable longstanding from inspiring English sources

However, there is considerable, longstanding international evidence indicating that PAAP implementation (issuing and review by professionals and use by patients/carers) is sub-optimal [ 8– 11] and needs to be improved if their clinical benefits are to be maximised.

In breast cancer there are clearly a number of factors that counter-intuitively influence outcome or for which there is a change, after a considerable time, in longstanding evidence that outcome was not affected.

Although the malignancy risk with anti-TNF therapy has been a concern because of the role of TNF in inhibiting tumour growth, this has not been borne out in studies of patients with RA. 41 43 There is, however, considerable evidence that longstanding chronic inflammation in the very patients who receive anti-TNF agents is itself related to an increased lymphoma risk.

Her tale of sniper fire generated considerable ridicule, with Christopher Hitchens (a longstanding critic of Clinton and her husband) concluding that she either "lies without conscience or reflection" or "is subject to fantasies of an illusory past" or both.

(Chinen) * BRAD MEHLDAU TRIO (Tuesday through Nov. 27) With "Day Is Done" (Nonesuch), the pianist Brad Mehldau has renovated the sound of his longstanding trio, with considerable help from the powerfully expressive drummer Jeff Ballard; the group's luminous brand of lyricism has survived, but its repertory is more pop-inflected, and its rhythmic push more pronounced.

Thus, artificial reprogramming of autologous somatic cells into vascular endothelial cells gives considerable new hope to overcome this longstanding obstacle.

The Veterans Affairs Diabetes Trial (VADT) (27) and Action to Control Cardiovascular Risk in Diabetes (ACCORD) studies failed to document a significant reduction of renal events by intensified glycemic control in type 2 diabetic patients, but a valid argument has been raised that these were patients with longstanding type 2 diabetes and considerable preexisting end-organ damage.

While Hilburn doesn't aspire to recast the Cash mythology — that mythology, after all, is as true and as essential to Cash's story as anything else — he does take considerable care to point out his subject's longstanding penchant for narrative embellishment.

Some of these are longstanding issues that have persisted despite considerable effort.

The North's threats were considerably more specific than past warnings and came just as American intelligence agencies expressed concern that the country may have made considerable progress in its nuclear and missile programs despite longstanding sanctions.

In the wake of the marriage equality victory in New York State, there has been considerable liberal and gay criticism of President Obama for his longstanding "I'm evolving" dodge.