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A population survey needs a considerable larger sample size than a microenvironmental survey because the unit of observation is an individual.
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The present study of serum levels of mood stabilizers and cognition is one of the first studies in a considerable large sample of psychosis spectrum patients, and although in need of replication, gives reason to believe that lamotrigine, valproate, and lithium can be administered across the dosage ranges without broad cognitive adverse effects.
Our data shows that even though under optimal conditions the variance of real-time QPCR is considerable across large sample numbers, however it still may have a place as purely a confirmatory assay for sequencing projects or MLPA and PRT data sets.
It shows that routine health care systems are rather inert and insensitive to change and that variability between and within health centers is considerable and perhaps requires larger sample sizes.
Other information theoretic methods that infer biological network connectivity from data sets with larger sample sizes[14], also involve a considerable effort to remove effects that are dominated by global correlations such as the use of the data-processing inequality[15].
Generalizations of this study's conclusions to all patients with early-stage ovarian tumors should be considered with caution, and there is still considerable need for higher quality studies with relatively larger sample sizes to address this topic.
But it is clear that although the present findings are of considerable significance they should be supported by the studies with larger sample.
These results indicate that a meta-analysis with larger sample size and hence statistical power results in a considerable increase in the detected cis-eQTL even though the arrays that had been used were different.
Comparing the muscle and brain samples, the gene expression changes in the muscle are often more significant and a considerable larger number of genes is found changed in muscle versus brain.
Perhaps with larger sample sizes.
But what did a larger sample think?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com