Sentence examples for considerable importance that the from inspiring English sources

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It is of considerable importance that the gene expression of the HNF4α target genes insulin1 (INS1) and insulin2 (INS2) was significantly repressed (Table 5).

Therefore, it is of considerable importance that the improvements, decision-making, and results presented must be grounded in reliable and valid data.

To ensure that we are identifying all vCJD cases, and also to ensure that the disease is not entering the human population by a more surreptitious route (eg via different animals, different strain of prion), it is of considerable importance that the Irish CJD Surveillance Unit continue to be notified of all possible cases of TSEs.

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"It is of considerable importance that politicians stick to their commitments or do not make such commitments in the first place.

It is of considerable importance that bilirubin, which is converted from biliverdin, a product of HO, significantly decreased the number of TUNEL-positive AH136B cells treated with ZnPP IX.

At the college he was named party secretary, a post of considerable importance that he held for three years.

It is of considerable importance that insufficiency subchondral fractures, osteonecrosis, and transient osteoporosis be differentiated, because their treatments and prognoses are quite different.

The fact that there is a population of Pakistanis that refuses to acknowledge that an issue such as acid burning is one of considerable importance that mandates exposure is indeed sad and indicative of a deep sense of denial.

It is of considerable importance that siRNA-mediated functional knockdown of FOXA2 resulted in transcriptional activation of HNF6 and of genes targeted by this factor.

It is of considerable importance that NFAT cooperates with other transcription factors involved in insulin transcription such as PDX1, NEUROD1 and HNF4α.

It is of considerable importance, that c-Myb regulates Igf2 (Figure 9), which allows tumor cells to develop an independent autocrine loop thereby integrating EGF and IGF-2 signaling networks [27], [28].

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