Exact(1)
General assessment: The mechanism of Her2 activation and signaling is of considerable importance considering its role in human disease (including cancer) and as a drug target.
Similar(59)
Considering the considerable importance of calcium as a second messenger, these observations open new avenues for understanding the role of CCN proteins in cell growth regulation.
However, the observed association may still be of considerable importance at a population level, considering the epidemic proportions of diabetes and the persistent lack of effective treatments for diastolic dysfunction and diastolic heart failure.
Especially in times of generally adequate diet, studies of epigenetic change may miss a factor of considerable importance if they do not consider chemical agents.
At one point, the league asked police to carry out surveillance on a meeting of trade unionists as the blacklisters considered it "of considerable importance".
Long-term durability of protective coatings is considered to be of considerable importance because fibers installed into outside plant networks are expected to have a minimum service lifetime of 25 years.
In any circumstances, Cp. psittaci has to be considered an underestimated pathogen with considerable importance in public health, although the various facets of its specific impact have yet to be evaluated.
It is also a contribution of considerable importance, for it invites us to follow Dahl in considering with intellectual precision and rigor some central dilemmas of democratic pluralism.
If one considers various methods of algorithmic composition, considerable importance can be allotted to differentiating between construction and resultant form, i.e., between compositional idea, its realization in the musical score, and its auditory perception.
Consequently, yellow fever is considered an emerging, or reemerging disease of considerable importance.
No one explicitly considers the tertiary structure information or protein localization, both of which are of considerable importance in vivo.
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