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Coastal regions also support considerable human populations; at least 50% of people on Earth live and work within 200 km of a coast [2].
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The remaining land separating the bears has seen considerable human alteration and population growth.
Indeed, TLR5392STOP is a non-functional allele that may reach considerable frequencies in some human populations (up to 23%; [ 65]) despite increasing the susceptibility to the Legionnaires' disease.
The Fmo3 gene has received considerable attention in studies of human populations, since it exhibits extensive polymorphism among individuals and may be a factor promoting differential drug response [ 51].
In other words, genetic differentiation across human populations explains a considerable amount of recombination differences among them.
Only human populations of a considerable size are able to sustain circulation [ 1].
Surveys of genetic diversity in indigenous human populations worldwide have documented considerable variation in the level of heterozygosity present within a population (Bowcock et al. 1994; Rosenberg et al. 2002; Prugnolle et al. 2005; Ramachandran et al. 2005).
Genetic studies in human populations are challenged by a considerable genetic heterogeneity which may explain why previous efforts have shown a non-significant heritability of nasal carriage of S. aureus [ 9, 10].
In addition, because of the long-range transport of DDT in the environment and its accumulation in the marine-food chain, human populations in the Arctic have had considerable exposure to DDT in their diet.
PFOS has been detected in human populations from all over the world, but considerable variation in exposure has been observed between populations (Lau et al. 2004).
Previous studies demonstrate that considerable natural variation in gene expression levels exists within and among human populations [49].
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