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A 2-way ANOVA model incorporating the donor ID (representing the three different genetic backgrounds of the transformed cells) as the additional factor revealed considerable gene expression changes between wtBAC and 3BKO LCLs (Table S5).
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It is noteworthy that even without exposure to any exogenous DNA damaging agents there is considerable gene expression change.
During the muscle transition between late foetal gestation and lamb at 4 months of age, there are considerable gene expression and physiological changes (Byrne et al. 2010).
Comparing the muscle and brain samples, the gene expression changes in the muscle are often more significant and a considerable larger number of genes is found changed in muscle versus brain.
Therefore, we referred the expression data from mature gland to investigate gene expression changes in epithelium.
And if there are changes, could they alter the laboratory conditions so those gene expression changes do not occur?
There is not enough information about MT gene expression changes in different grade gliomas.
Hu, J. et al. Heterogeneity of tumor-induced gene expression changes in the human metabolic network.
Ament, S. A. et al. Transcriptional regulatory networks underlying gene expression changes in Huntington's disease.
The concept of gene scores to reflect severity of gene expression changes is not new.
After a python eats, its gene expression changes rapidly.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com