Sentence examples for considerable functional and from inspiring English sources
While most wounds heal with a scar that is acceptable to the patient, large scars cause considerable functional and cosmetic deformities, as well as psychological stress, and patient dissatisfaction.
Furthermore, in p63 and p73 family members, a large number of C-terminal splice variants exist that add considerable functional and structural diversity.
While CD34-DC may be more powerful vaccine vehicles than the more commonly used MoDC, the use of in vitro generated CD34-DC is complicated by the lenghty and laborious methodologies involved, considerable functional and phenotypic variability between batches (both intra- and inter-individual) and the extremely low frequency of CD34+ DC precursor cells in peripheral blood.
Pediatric anxiety disorders have high prevalence rates and morbidity and are associated with considerable functional impairment and distress.
As we note above, Dichaete and mammalian Sox2 show considerable functional similarity and recently, a genomic study identified over ~1400 Sox2 target genes in neural stem cells [ 61].
Programs of considerable functional, contextual, and conceptual complexity are undertaken.
However, the not very well-conserved primary sequences reflect considerable functional diversity and different protein interactions.
Depressive illness results in considerable functional disability and decreased quality of life, particularly for older people.
Macrophages display considerable functional plasticity and immediately respond to changes in their microenvironment [ 5, 13].
Anxiety disorders are associated with considerable functional impairment and reduced quality of life; this is especially true for comorbid presentations that are characterized by more severe impairment and poorer response to treatment.
Inclusion or exclusion of different domains in this region can thus generate considerable functional diversity, and up to 22 human splice variants have been identified by RT-PCR analysis [ 19].
