Sentence examples for considerable fold from inspiring English sources

The rationale behind the selection of the cutoff for considerable fold difference while comparing the gene expression is based on standard practice in microarray data analysis [ 5- 10].

From our findings, miR-17 family (hsa-miR-17, hsa-miR-18a, and hsa-miR-106b) triggered higher expression with significant P values (<0.05) and considerable fold changes (>1.0 fold) both in serum and tumor miRNA profiles.

The first two transcripts are prominent due to the considerable fold change expression ratios of 20.9 and 21.7 (up) (Additional file 1) and their up-regulation exclusively in the FHB treated spikes of cv.

Among these Ta.7843.1.S1_a_at (Table 5) seems to be an interesting resistance candidate, as the gene combines a general high antifungal property with considerable fold change expression ratios at both timepoints (Additional file 1).

Comparison of the Zn2+-bound SitA structure with another zinc-bound SBP, the E. coli protein ZnuA, revealed considerable fold similarity (rmsd 2.2 Å) but to a lesser extent than when comparing SitA with the Mn2+-binding protein PsaA (see above and Supplementary Figure S5).

Based on the criterion B>0, no significantly DE genes were found in the offspring, although there were several genes with considerable fold-changes, i e, the estimated average expression levels were higher in one of the treatments.

14, 29 In this study, such an increase in titers after the third dose was not observed; however, because the sample size is small and the assay variability is considerable, a fold difference of less than two is not significant enough to characterize it as higher or lower.

Unexpectedly, employees who had one or more absence for psychiatric reasons had a considerable 2.5-fold greater cancer mortality.

However there is considerable (>three-fold) uncertainty in the range of concentrations obtained from in vitro cell-based assay that are required for maximal binding (6 to 20 μg ml−1 and 1 to 3 μg ml−1, respectively).

At an assay concentration of 40 μg/mL, this variant showed a considerable (∼450-fold) reduction in its kcat from that of wt BFDC, but it was impossible to say whether this was a reflection of the presence of tetramer in solution or the dimer indeed retained some activity.

The extra information utilized by the new methods has led to considerable improvements in fold recognition and alignment accuracy.