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However, despite substantial improvements in the efficiency of "next generation" technologies, undertaking deep re-sequencing remains a considerable financial undertaking in the large sample sizes needed to localise the causal variants of modest effect size we expect for T2D susceptibility.
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However, few RCTs have been performed on CAMs as there is little incentive for manufacturers to undertake the considerable financial investments required for phase 1 4 clinical trials that assess efficacy, effectiveness, safety and cost-effectiveness [ 5] when individual CAMs may be provided by several providers and can not be protected by patent.
Within the Australian public hospital system it is being recognised that, as in the UK, appropriate utilisation of the skills of nurses and expansion of their role to undertake routine, low-risk procedures usually performed by doctors could lead to considerable financial savings and benefits for both patients and staff [ 21].
Hulsizer is taking on considerable financial risk.
Success brought Irons considerable financial reward.
Jefferies has received considerable financial compensation.
Senior professionals can expect considerable financial rewards.
It would be a considerable financial burden to bear alone.
Selling direct to consumers has given Dell considerable financial advantages.
The Mets are certainly under considerable financial pressure.
It also translated into considerable financial losses: $54 million.
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