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However, statistical analysis of the identified microRNA-mRNA interactions indicated a considerable false positive rate.
This, we assume, was partially due to the considerable false positive rate in the HapMap 3 data.
For example, a naïve Bayesian model for SNP calling even with deep coverage can lead to considerable false positive rates [ 38].
Our results demonstrate that Mycoplasma hyorhinis infection can play an important role on cultured human colon cancer cell lines giving rise to considerable false positive increase of CSCs cellular fraction characterized by CD133 expression.
These results indicate that the non-randomness of the sample may result in considerable false positive or false negative inference of the disequilibrium parameter and, in turn, false positives or false negatives in association analyses in which significant degree of marker-disease association implies significant linkage disequilibrium.
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If the "bereavement exclusion" is eliminated, they say, "there is the potential for considerable false-positive diagnosis and unnecessary treatment of grief-stricken persons".
For example, a recent study on the exon array showed that the effect of SNPs was quite severe and could lead to considerable false-positive findings [20].
With the dideoxy blocker, there was an improvement but still considerable false-positive amplification (see Figure 4; panel B).
However, network-based identification of disease-related genes is still a challenge as the considerable false-positives are still existed in the current available protein interaction networks (PIN).
Although great progresses have been made on the network-based methods, it is still a challenge task to identify disease-related genes as the considerable false-positives are still existed in the current available PINs [ 25].
Although using the CSPS alone might result in considerable false-positives, personnel workload, and extra resources allocated in staff training, it was evident that the scale was comparatively an appropriate option for suicide risk prediction than other scales tested in our study.
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