Exact(11)
While the small overlap seems to be surprisingly low, small overlaps between interaction datasets are commonly observed, and may be explained by the large phylogenetic distance between these species, the different methodologies applied, the considerable false negative rate, and the incomplete sampling of each interactome.
However, statistical analysis of the identified microRNA-mRNA interactions indicated a considerable false positive rate.
Diagnostic thresholds current disregard for subthreshold, subsyndromal and subclinical symptoms may lead to considerable false negative cases.
Generally, SICER demonstrated a high sensitivity of predictions (recall = 87.4%) together with a considerable false discovery rate (Precision = 79.8%).
This, we assume, was partially due to the considerable false positive rate in the HapMap 3 data.
For example, a naïve Bayesian model for SNP calling even with deep coverage can lead to considerable false positive rates [ 38].
Similar(49)
If the "bereavement exclusion" is eliminated, they say, "there is the potential for considerable false-positive diagnosis and unnecessary treatment of grief-stricken persons".
For example, a recent study on the exon array showed that the effect of SNPs was quite severe and could lead to considerable false-positive findings [20].
The trade-off of this attempt, however, certainly was a considerable false-negative rate.
With the dideoxy blocker, there was an improvement but still considerable false-positive amplification (see Figure 4; panel B).
However, network-based identification of disease-related genes is still a challenge as the considerable false-positives are still existed in the current available protein interaction networks (PIN).
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