Sentence examples for considerable failure rates from inspiring English sources

Studies showed considerable failure rates related to loss of retention when using water-based cements and clinical evidence supports the importance of adhesive cementation for the long-term success of all-ceramic restorations and prostheses [6 8].

Current therapy-regimens against Helicobacter pylori (Hp) infections have considerable failure rates and adverse side effects that urge the quest for an effective alternative therapy.

The LNG-IUS can be applied easily by the general practitioner, which saves costs, but has considerable failure rates.

This does not come under surprise since oncology products due to their innovative mode of action status, high R & D costs and considerable failure rates ask for higher prices.

Usual care in The Netherlands implies two strategies for the treatment of heavy menstrual bleeding if drug therapy fails: first, there is the LNG-IUS that can be applied easily by the GP, which saves costs, but has considerable failure rates.

Spinal anesthesia by the lateral approach also has a considerable failure rate [ 8].

Such controllable aspects of the environment as location of work and working hours can have a considerable effect on productivity and failure rates.

The approach also gives more insight into the considerable uncertainty in failure rate estimates based on small sample sizes.

However, regimens that require considerable parental or patient attention will have higher failure rates.

Failure rates due to complications are still considerable, although the implants and surgical techniques have improved greatly.

Although intraoperative radiation therapy (IORT) has been introduced in some centers to overcome the dose limitations and resulted in increased outcome [ 3], local failure rates are still high even if considerable treatment related toxicity is accepted [ 2, 3].