Sentence examples for considerable evidence now from inspiring English sources

Considerable evidence now indicates that renal inflammation plays a central role in the initiation and progression of CKD.

While considerable evidence now exists demonstrating the efficacy of the Wii Fit, no study to date has determined the specific mechanism underlying Wii Fit balance improvement.

Considerable evidence now exists to support the beneficial effects of physical activity (PA) for human health and wellbeing [1 3].

Considerable evidence now exists for the biallelic expression of certain imprinted genes in undifferentiated human ES cell lines, however.

Considerable evidence now indicates that the tip link is composed of two proteins, protocadherin 15 (PCDH15) and cadherin 23 (CDH23).

The tectum a multisensory, topologically mapped structure in the roof of the midbrain presents a remarkable degree of conservation in all vertebrate radiations [1]; although it varies in the extent of its development in different vertebrate classes, there is considerable evidence now to deem its layered structure, its cell types, and its hodological pattern as homologous in all vertebrates.

However, considerable evidence is now emerging that, as expected, these targeted drugs are not agent specific and that they are likely to improve the efficacy of both irinotecan and oxaliplatin combinations.

Considerable evidence has now accumulated for tumour-associated macrophages stimulating key aspects of tumour progression, including the proliferation, survival and metastasis of tumour cells, tumour angiogenesis and suppression of the anti-tumour functions of other immune effectors at the tumour site.

Considerable evidence has now accrued through application of a broad range of technologies to a wide spectrum of in vitro and in vivo model systems to substantiate XIAP as a valid molecular target in cancer therapeutics (Lacasse et al, 2005; Wright and Duckett, 2005; Schimmer et al, 2006).

A considerable body of evidence now supports the 'neurogenic' hypothesis (Donaldson et al., 1995; Rees et al., 1996; Decaris et al., 1999).

There is now considerable evidence that associates increased breast cancer risk with prolonged exposure to oestrogens hence greater attention is now being given to determining whether the measurement of plasma oestrogen may assist in identifying chemoprevention target groups.