It represents a considerable emerging infectious disease threat because of its consequences to human health and the difficulties in preventing and controlling it (2, 3 ).
As there is also considerable emerging evidence that dual inhibition of the PI3K and ERK pathways is more effective at inhibiting tumourigenesis than inhibition of either pathway alone (She et al, 2005; Carracedo et al, 2008; Engelman et al, 2008), it may therefore be necessary to combine these inhibitors with an inhibitor of the ERK pathway.
There is considerable controversy emerging regarding the use of ESWT for plantar heel pain.
Its difficulties, and they are considerable, will emerge later on.In this section How strong is China's economy?
Considerable laughter emerges out of the terrible circumstances that surround Aron and his family, as the only defence the Jews of Warsaw have against patented insanity, and it rings convincingly with the syntax and speech patterns of aphoristic Yiddish wit.
Over the course of the year, considerable evidence emerged that the Bush administration did what seemed unthinkable: it used federal prosecutors, who are supposed to be scrupulously nonpartisan, to help the Republican Party win elections.
He was declared the winner of that election, which was initially certified by some international observers as free and fair but later marred as reports of considerable fraud emerged.
Considerable variability emerged in the way adolescents satisfied their personal needs online and offline, in the experienced impact from high online engagement and functional value ascribed to the internet, and in the self-regulatory processes underlying use.
However, considerable difficulties emerge in case of urea used, which consist in high hygroscopicity and caking, reduction of the amide nitrogen proportion in the product due to decomposition of urea at relatively low temperatures during granulation and drying, and complexity of the technological process because of heavy clogging of equipment [10, 11].
Considerable differences emerged between the policy institutes in how their agenda of work was developed, and the extent to which their governance and financing arrangements made them responsive to government.
Extracellular strategies are mostly missing although considerable knowledge emerged that the composition and rigidity of the ECM, and consequently ECM cell signaling plays an important role in cancer progression 22, 23.
