Sentence examples for considerable effort has been expended from inspiring English sources
Considerable effort has been expended on developing deep geological repositories for radioactive waste (RAW) associated with energy production and industry.
Since the original approval of dacarbazine for the treatment of metastatic malignant melanoma, considerable effort has been expended in attempts to improve survival.
Moreover, considerable effort has been expended to ensure that dispersion in the structural response due to usage of different earthquake records is minimized.
In most countries, the documentation suggests that considerable effort has been expended on enumerating them and making practical and conceptual adaptations to their mobility to include as many as possible.
While considerable effort has been expended in the study of the response of non-pressurized spacecraft components to these kinds of impacts, relatively few studies have been conducted on the pressurized elements of such spacecraft.
At the same time, EU member states are committed to reducing the number of animals used in experiments under the 3 Rs policy (refining, reducing, and replacing the use of animals in laboratory procedures), and so considerable effort has been expended on searching for alternative methods of assessing the human and environmental safety of these compounds.
Although considerable effort had been expended in distributing letters, leaflets and posters to every general practice, less than half the respondents said they had seen it.
Since the majority of available conventional antibiotics do not exhibit prolonged effects, considerable efforts have been expended to demonstrate different antibacterial agents such as metal nanoparticles for wound dressings, drug delivery platforms, and tissue engineering scaffolds.
Therefore, considerable efforts have been expended to analyze the performance of the algorithm as a function of uncertainties of MISR surface reflectances and to establish the convergence property of the MISR LAI/FPAR algorithm, namely, that the reliability and accuracy of the retrievals increase with increased input information content and accuracy.
As NCL in its original version is cysteine dependent, considerable efforts have been expended toward the development of cysteine-free ligation methods, 9 while others aimed to convert the erstwhile cysteine into an alanine to circumvent the requirement for cysteine in the proposed ligation site.
