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More importantly, the pipeline filtered out SNPs that did not belong to the same exon by using the draft genome sequence for E. grandis, therefore avoiding failures due to SNP located in intron/exon junctions, a considerable drawback when developing SNPs from ESTs [ 51].
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Opioid analgesic tolerance remains a considerable drawback to chronic pain management.
The one (considerable) drawback is that the road off the A87 to Glenelg is narrow, banked and not for the vertiginously challenged, with many steep switchbacks.
P. californiensis' approach has one drawback: when a bubble is disturbed it quickly collapses.
The 1GB of memory is a big drawback when running Windows and Microsoft Office.
One drawback: when you're not on a call, the headset rests on your chest.
However, the policy suffers from a drawback when the land that the government needs is owned by many parties.
Eligible spirits become "subject to drawback" when they are used in the manufacture of a nonbeverage product.
The most considerable drawback represents controlling and optimizing the quality of the CNT/metal contact.
While the arguments mentioned above reduce this problem, it remains a considerable drawback to some experimental evidence.
Drawback: When I finally hit the sack, I tossed and turned all night.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com