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To our knowledge, "loss-of-function" studies of DUBs in any kinds of organism have been carried out only for very few genes due to the considerable cost associated with raising genetic knockout- and/or knockdown-modulated animals.
Only two studies performed separate estimations of the intangible costs; these studies reported a considerable cost associated with pain and suffering (about $5 billion for Canada and US $46.84 on average per capita for France).
Given the considerable cost associated with these techniques and the fact that the majority of transmission events in non-epidemic settings are probably not mediated by the environment, it seems advisable for now to continue to invest most effort into traditional infection control measures such as hand hygiene and wait for further evidence before introducing these techniques into routine care.
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While fully aware of the considerable costs associated with producing musicals, I kept fantasizing about investors' underwriting not just scenery and costumes but also cheaper tickets, so that catching a show with your kids wouldn't feel like such a financial commitment.
found that there are considerable costs associated with treatment of complications due to isolated ankle fracture [6].
It also carries a heavy economic burden, with considerable costs associated with primary care and loss of income.
Although this impact on downstream flooding may apply only up to a threshold, any relief would be welcome given that considerable costs associated with flooding, especially in catchments containing urban areas.
4 Also, there are considerable costs associated with conducting an RCT.
Besides the psychological and physical burden of each IVF treatment cycle, it also adds to the considerable costs associated with fertility treatment [ 1].
Third, we did not include comprehensive data on health resource utilization, and there may be considerable costs associated with hospital medication use and procedures not included.
However, the considerable costs associated with archiving the mice, supporting the informatics and project organization are still provided from a European Commission FP7 grant as well as national research programmes and institutional funds at individual partner sites.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com