Sentence examples for considerable copy number from inspiring English sources

Other interesting genes located within regions with considerable copy number differences among populations include several that were previously known to be variable and associated to different biomedical conditions (GSTT1, UGT2B17, PRSS2 and APOBEC), as well as others that, although associated to disease phenotypes, have not been reported to be variable among populations.

This caused considerable copy number variation among plant species.

Due to their considerable copy number in the genome, causality or even contribution may be more difficult to establish for many HERVs than for single etiologic agents.

The defective sir2Δ gene causes an rDNA hyper-recombinogenic phenotype that has considerable copy number variation (Fig. 2B, Gottlieb & Esposito 1989; Kobayashi et al. 2004).

Revolver exhibits structural diversities and considerable copy number variation through the evolution of the Triticeae, from 2 × 10 in rye to almost rare in wheat.

Zeiger et al. measured the expression levels of telomerase reverse transcriptase (hTERT) in follicular tumours and showed that this method was to some extent useful in diagnosing follicular carcinomas, although they also described interference due to contamination by lymphocytes, which expressed a considerable copy number of hTERT mRNA (Zeiger et al, 1999).

A similar study of clinal adaptation in Drosophila melanogaster also found a considerable contribution of copy number variation to population differentiation, including large variants that affected multiple genes [17].

These TRs exhibit considerable variation in copy number and motif length, with the former ranging from 2 to 158 copies, and the latter from 1 bp to 478 bp.

There is a clear positive correlation between the two methods, and it is also clear that the PRT generates data that clusters effectively into integer copy numbers, particularly at lower copy numbers, in contrast to aCGH where there is considerable overlap of copy number classes.

A potential cause of ASGE might be the considerable variation in gene copy number in the human genome [21].

The considerable variation of Revolver copy number among the wheat-related species indicates their propagation activity during evolution of the Triticeae tribe.