Sentence examples for considerable clinical efficacy from inspiring English sources
Results from this phase II study suggest that the addition of cetuximab to first-line doublet carboplatin and weekly docetaxel results in a considerable clinical efficacy with an acceptable toxicity profile for patients with advanced or metastatic NSCLC.
ErbB2-targeted therapies, particularly humanized monoclonal antibody trastuzumab, have shown considerable clinical efficacy.
Additionally, pharmacokinetics data suggest that in adults a dose of 30 mg kg−1 can be administered for a prolonged period without toxicity and possibly with considerable clinical efficacy.
Although it is valid to reason that the current antimitotics are targeting only a limited fraction of cells within a tumor population, it still does not explain how taxanes achieved considerable clinical efficacy by similarly affecting the propagation of mitosis.
Although PPARγ antagonists have shown considerable pre-clinical efficacy, recent studies suggest PPARγ ligands induce PPARγ-independent effects.
Cardiac cell therapy and tissue engineering have attracted considerable attention and clinical trials are ongoing to assess clinical efficacy and accommodate translation to the clinic.
"PrEP is an intensive intervention for which cost, feasibility, and behavioral considerations may be as important as clinical efficacy".
Strategies to invoke or augment cellular anti-lymphoma immune responses may also have considerable therapeutic potential and serve to further augment the clinical efficacy of MAbs.
Despite the considerable clinical and economic implications, the evidence on the true efficacy of many orthopedic procedures is at best scarce.
With proven preclinical efficacy, it is anticipated that STX243 will have considerable clinical potential in treating patients with various oncological conditions.
Owing to their molecular differences, these agents demonstrate considerable variation in their pharmacokinetic and pharmacodynamic properties, which are likely to affect clinical efficacy [ 70].
