Sentence examples for considerable challenges when from inspiring English sources

Estimation of treatment effects in economic evaluation involves considerable challenges when observational data are used.

In the managed care setting, pharmacy benefit managers face considerable challenges when making decisions regarding drug coverage.

An imaging facility with a diverse fleet of CT scanners faces considerable challenges when propagating CT protocols with consistent image quality and patient dose across scanner makes and models.

Low temperature of cryogenic propellant components may pose considerable challenges when chilling down, fueling and storing components as well as draining fuel tanks and starting PS, especially under zero gravity conditions in long-term space flights.

The large databases of structures and properties that result from computational searches, as well as the agglomeration of data of heterogeneous provenance leads to considerable challenges when it comes to navigating the database, representing its structure at a glance, understanding structure property relations, eliminating duplicates and identifying inconsistencies.

Laboratories that conduct sequencing-based tests currently encounter considerable challenges when delivering useful interpretive reports.

Screening the memorial from the impact of over 100 trucks an hour entering the ramp "will be a considerable challenge when designing the space," the draft guidelines noted.

This overlap presents a considerable challenge when trying to determine the concentration and proportion of a particular dye at a given spatial location where two dyes have been mixed.

However, the design of autonomous decision-making systems presents considerable challenges, particularly when they have to achieve their goals within a dynamic context.

In principle this sounds encouraging, but there are considerable challenges even when developers are keen to abide by the spirit as well as the letter of local guidelines.

However, considerable challenges exist when developing and using PT in the evaluation of complex interventions, not least, the resources required [ 5], the ability to achieve stakeholder engagement and consensus [ 5], and the ability to usefully represent a complex reality in a simple model [ 10].