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While any duration of hormone therapy can delay the risk of osteoporosis and fractures, once estrogen is stopped, considerable bone loss can occur rapidly.
Microgravity research on the ISS has demonstrated that the human body would lose considerable bone and muscle mass on such a mission.
However, restraining biomechanical issues such as considerable bone loss around the stem and peri-prosthetic bone fractures are present.
The patients also participated in a randomised study of 40 patients with the aim of evaluating the use of trabecular metal cones (Zimmer) for reconstruction of considerable bone loss of the proximal tibia in rTKA.
It is also the first report confirming that the GBR technique could be effective for treating long tubular bone defects, which remains a challenge for orthopaedic surgeons, and it may enable superior bony union across a considerable bone defect gap of almost 15 mm.
Clinical outcome after 1 year of follow-up was comparable with other studies on rTKA with considerable bone loss, where bone loss at the proximal tibia and/or femur was reconstructed with stemmed femoral implants and impaction bone grafting [12, 13] with or without metal augments [14].
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The defects that were left empty showed considerable more bone growth in normal bone than in osteoporotic bone.
All groups had considerable new bone formation on the pressure side.
In all groups, considerable new bone formation was observed on the pressure side after 6 weeks.
During removal of the stem, considerable periprosthetic bone loss was found at the distal part of the stem.
Aseptic loosening is the most common glenoid-sided complication requiring revision following RSA (Fevang et al. 2009), and is often associated with considerable scapular bone loss (e.g. inferior scapular notching, glenoid deficiency after implant removal), which further complicates surgical revision (Antuna et al. 2001, Boileau et al. 2005, Elhassan et al. 2008, Gerber et al. 2009).
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CEO of Professional Science Editing for Scientists @ prosciediting.com