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The receptor 1 is found to have considerable binding affinity for weakly basic anions even in polar solvent such as DMSO.
These two compounds displayed extra precision docking scores of -7.972908 and -7.575686 respectively suggesting considerable binding affinity for cathepsin L. High activity values of 5.72 and 5.75 predicted using the 3D QSAR model further substantiated the inhibitory potential of these identified leads.
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However in the absence of endogenous Bub1 considerable binding affinity is regained.
And two of the designed aminoacyl-tRNA synthetases had considerable binding affinities.
Among 60 mutated aminoacyl-tRNA synthetases, 15 of them showed binding ability to p-acetyl-L-phenylalanine, of which two had considerable binding affinities.
Binding affinity in both human and canine prostate most significantly correlated with binding affinity for the recombinant bovine alpha-1C receptor (r =.98 human,.95 canine).
The presence of the toxic enzyme inside the cocoon is essential for its subnanomolar binding affinity for the TcA subunit.
Direct mutation of predicted interface residues confirmed that the protein had altered binding affinity for the mannose 6-phosphate receptor.
One mutant, MR1-1 scFv), had increased specific binding affinity for EGFRvIII.
c Targets detected with no significant binding affinity for CIS22a.
Immunomodulatory peptides with high binding affinity for class II MHC molecules for the prevention of graft-versus-host disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com